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In the groups treated with highest doses, the ovarian weight remained unchanged. It is well documented that the AAS promotes reduction in reproductive organ weights (Camargo et al, meso-rx steroids. The suppression of estrous cyclicity caused by AAS treatment was previously reported in various studies (Gerez et al. According to Karbalay?Doust and Noorafshan (2012), administration of exogenous steroids may increase circulating androgen levels, thus altering the control of the hypothalamus’pituitary’gonad axis which results in altered levels of hormones, such as follicle?stimulating hormone (FSH), luteinizing hormone (LH), oestrogen and progesterone (Bronson et al. Moreover, these hormonal disturbances may affect the regulation of the estrous cycle as observed.
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