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They will be recruited by 10 hospitals in China. The Intervention group takes JZOL and Ambroxol Hydrochloride and Clenbuterol Hydrochloride Oral Solution (AHCHOS) placebo, while the control group receives AHCHOS and JZOL placebo. The dosage of the two drugs varies according to age and weight. The medication lasts for 7 days. Clenbuterol is a kind of β2-adrenergic receptor agonists, and clenbuterol hydrochloride is clinically used as anti-asthmatic agent that belongs to a broad group of drugs known as sympathomimetics [ 6 ]. It is commonly used because of its anabolic effects and the ability to promote lipolysis [ 7 ]. DS Syrup: Adults and Children >12 years: 5 mL thrice daily for 2-3 days then 5 mL twice daily for 2. 5 mL thrice daily. Children 6-12 years: 2. 5 mL 2-3 times a day. Infant Drops: Children 13-24 months: 1. 25 mL twice a day; 7-12 months: 1 mL twice a day; ≤6 months: 0. 5 mL twice a day. Ambroxol (2-amino-3,5-dibromo- N — [trans-4-hydroxycyclohexyl] benzylamine) is considered a mucoactive agent and has been widely used to treat acute and chronic respiratory diseases since 1978 [ 8 ]. They received 30 mg of ambroxol alone (one Fluibron tablet), or 20 micrograms of clenbuterol alone (one Spiropent tablet), or 30 mg of ambroxol plus 20 micrograms of clenbuterol in combination (one CHF-023 tablet), every 12 hours for 7 days on three separate occasions. Ambroxol is a medication indicated for airway secretion clearance therapy. Generic Name Ambroxol DrugBank Accession Number DB06742 Background. Ambroxol is a secretolytic agent used in the treatment of respiratory diseases associated with viscid or excessive mucus. It is the active ingredient of Mucosolvan, Lasolvan or Mucoangin It is important to start at a low dosage and gradually increase it to avoid side effects, ambroxol clenbuterol dosage.
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